Decreased expression of TIPE2 contributes to the hyperreactivity of monocyte to Toll-like receptor ligands in primary biliary cirrhosis
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- 作者：Baodong Qin ; Tingting Wei ; Lili Wang ; Ning Ma ; Qingqin Tang ; Yan Liang ; Zaixing Yang ; Lin Zhou and Renqian Zhong
- 刊名：Journal of Gastroenterology and Hepatology
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：31
- 期：6
- 页码：1177-1183
- 全文大小：733K
- ISSN：1440-1746
文摘
Previous studies have shown differential TIPE2 expression in several autoimmune diseases. However, the expression levels of TIPE2 in primary biliary cirrhosis (PBC) remained unclear. The purposes of this study were to evaluate TIPE2 expression levels in patients with PBC and further investigate its role in PBC pathogenesis.