Mesenchymal stem cells have antifibrotic effects on transforming growth factor-β1-stimulated vocal fold fibroblasts

详细信息    查看全文

• 作者：Nao Hiwatashi ; Renjie Bing ; Iv Kraja and Ryan C. Branski
• 刊名：The Laryngoscope
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：127
• 期：1
• 页码：E35-E41
• 全文大小：504K
• ISSN：1531-4995

文摘

Mesenchymal stem cells (MSCs) hold therapeutic promise for vocal fold scar, yet the precise mechanism(s) underlying tissue level changes remain unclear. We hypothesize that MSCs interact with native fibroblasts to favorably affect healing. Furthermore, we hypothesize that these interactions vary based on MSC source.