Development of a MALDI MS-based platform for early detection of acute kidney injury
详细信息 查看全文
- 作者：Emma Carrick ; Jill Vanmassenhove ; Griet Glorieux ; Jochen Metzger ; Mohammed Dakna ; Martin Pejchinovski ; Vera Jankowski ; Bahareh Mansoorian ; Holger Husi ; William Mullen ; Harald Mischak ; Raymond Vanholder and Wim Van Biesen
- 刊名：PROTEOMICS - Clinical Applications
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：10
- 期：7
- 页码：732-742
- 全文大小：547K
- ISSN：1862-8354
文摘
Septic acute kidney injury (AKI) is associated with poor outcome. This can partly be attributed to delayed diagnosis and incomplete understanding of the underlying pathophysiology. Our aim was to develop an early predictive test for AKI based on the analysis of urinary peptide biomarkers by MALDI-MS.