Transient severe tricuspid regurgitation after transplantation of an extremely oversized donor heart in a child—Does size matter? A case report

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• 作者：J. Birnbaum ; S. M. Ulrich ; R. Schramm ; C. Hagl ; A. Lehner ; M. Fischer ; N. A. Haas and B. Heineking
• 刊名：Pediatric Transplantation
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：21
• 期：1
• 全文大小：385K
• ISSN：1399-3046

文摘

In pediatric heart transplantation, the size of the donor organ is an important criterion for organ allocation. Oversized donor hearts are often accepted with good results, but some complications in relation to a high donor-recipient ratio have been described. Our patient was transplanted for progressive heart failure in dilated cardiomyopathy. The donor-to-recipient weight ratio was 3 (donor weight 65 kg, recipient weight 22 kg). The intra-operative echocardiography before chest closure showed excellent cardiac function, no tricuspid valve regurgitation, and a normal central venous pressure. After chest closure, central venous pressure increased substantially and echocardiography revealed a severe tricuspid insufficiency. As other reasons for right ventricular dysfunction, that is, myocardial ischemia, pulmonary hypertension, and rejection, were excluded, we assumed that the insufficiency was caused by an alteration of the right ventricular geometry. After 1 week, the valve insufficiency regressed to a minimal degree. In pediatric heart transplant patients with a high donor-to-recipient weight ratio, the outlined complication may occur. If other reasons for right ventricular heart failure can be ruled out, this entity is most likely caused by an acute and transient alteration of the right ventricular geometry that may disappear over time.