Electrospinning: A Bioinspired Ultraporous Nanofiber-Hydrogel Mimic of the Cartilage Extracellular Matrix (Adv. Healthcare Mater. 24/2016)
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- 作者：Florian A. Formica ; Ece Ö ; ztü ; rk ; Samuel C. Hess ; Wendelin J. Stark ; Katharina Maniura-Weber ; Markus Rottmar and Marcy Zenobi-Wong
- 刊名：Advanced Healthcare Materials
- 出版年：2016
- 出版时间：December 21, 2016
- 年：2016
- 卷：5
- 期：24
- 页码：3216
- 全文大小：3712K
- ISSN：2192-2659
文摘
M. Zenobi-Wong and co-workers develop cell-seeded, ultraporous composite scaffolds for cartilage regeneration on page 3129. By means of cryoelectrospinning, ice crystals are co-deposited with the polymer. After sublimation, macropores are created which subsequently allow the infiltration of the electrospun membrane with a cell/hydrogel suspension. This procedure provides mechanical stability to the weak but chondrogenic alginate sulfate hydrogel.