Nanogels as Contrast Agents for Molecular Imaging

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• 作者：Jianzhi Zhu ; Wenjie Sun and Xiangyang Shi
• 刊名：Chinese Journal of Chemistry
• 出版年：2016
• 出版时间：June, 2016
• 年：2016
• 卷：34
• 期：6
• 页码：547-557
• 全文大小：2254K
• ISSN：1614-7065

文摘

Nanogels (NGs) as soft nanosized materials have gained a variety of interests in biomedical fields. The versatile NG scaffolds with 3-dimensional spherical shape, high loading efficiency, tunable surface functionalization, and excellent biocompatibility afford their uses as carrier to load mono- or multi-mode molecular imaging contrast agents (CAs). This review summarizes the synthesis routes and applications of NGs as CAs for molecular imaging applications including magnetic resonance (MR), computed tomography (CT), radionuclide, optical, and dual/multi-modality imaging.