Effect of Dietary Omega-3 Fatty Acids on Tumor-Associated Macrophages and Prostate Cancer Progression

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• 作者：Pei Liang ; Susanne M. Henning ; Shiruyeh Schokrpur ; Lily Wu ; Ngan Doan ; Jonathan Said ; Tristan Grogan ; David Elashoff ; Pinchas Cohen and William J. Aronson
• 刊名：The Prostate
• 出版年：2016
• 出版时间：October 1, 2016
• 年：2016
• 卷：76
• 期：14
• 页码：1293-1302
• 全文大小：1517K
• ISSN：1097-0045

文摘

Preclinical and clinical studies suggest that a fish oil-based diet may play a role in delaying the progression of prostate cancer through a number of different mechanisms involving inflammatory pathways. Given the importance of tumor-associated macrophages (TAMs) in carcinogenesis, we hypothesized that a fish oil-based diet will inhibit TAM infiltration and delay the growth of prostate cancer.