Engineered Nanoplatelets for Enhanced Treatment of Multiple Myeloma and Thrombus
详细信息 查看全文
- 作者：Quanyin Hu ; Chenggen Qian ; Wujin Sun ; Jinqiang Wang ; Zhaowei Chen ; Hunter N. Bomba ; Hongliang Xin ; Qundong Shen and Zhen Gu
- 刊名：Advanced Materials
- 出版年：2016
- 出版时间：November 16, 2016
- 年：2016
- 卷：28
- 期：43
- 页码：9573-9580
- 全文大小：2366K
- ISSN：1521-4095
文摘
A platelet-membrane-coated biomimetic nanocarrier, which can sequentially target the bone microenvironment and myeloma cells to enhance the drug availability at the myeloma site and decrease off-target effects, is developed for inhibiting multiple myeloma growth and simultaneously eradicating thrombus complication.