ChemInform Abstract: A Mild and Fast Continuous-Flow Trifluoromethylation of Coumarins with the CF3 Radical Derived from CF3SO2Na and TBHP.

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• 作者：Xiaodan Zhang ; Ping Huang ; Yaming Li and Chunying Duan
• 关键词：benzopyran derivatives ; regioselective reactions
• 刊名：ChemInform
• 出版年：2016
• 出版时间：March, 2016
• 年：2016
• 卷：47
• 期：12
• 全文大小：25K
• ISSN：1522-2667

文摘

A fast and mild conversion of coumarin to 3-trifluoromethyl-coumarin in a continuous flow reactor using inexpensive sodium triflate as the trifluoromethylation reagent is developed.