ChemInform Abstract: One-Pot Preparation of Trifluoromethylated Homoallylic N-Acylhydrazines or -Methylene--lactams from Acylhydrazines, Trifluoroacetaldehyde Methyl Hemiacetal, Allyl Bromide and Tin.
文摘
Whereas the title transformation using allyl bromide or 3,3-dimethylallyl bromide delivers trifluoromethylated homoallylic N-acylhydrazines, application of methyl-2-(bromomethyl)acrylate produces α-methylene-γ-lactams.