Palladium-Catalyzed Tandem Oxidative Arylation/Olefination of Aromatic Tethered Alkenes/Alkynes
详细信息 查看全文
- 作者：Yang Gao ; Yinglan Gao ; Dr. Wanqing Wu ; Prof. Dr. Huanfeng Jiang ; Xiaobo Yang ; Wenbo Liu and Prof. Dr. Chao-Jun Li
- 刊名：Chemistry - A European Journal
- 出版年：2017
- 出版时间：January 18, 2017
- 年：2017
- 卷：23
- 期：4
- 页码：793-797
- 全文大小：656K
- ISSN：1521-3765
文摘
We describe herein a palladium-catalyzed tandem oxidative arylation/olefination reaction of aromatic tethered alkenes/alkynes for the synthesis of dihydrobenzofurans and 2 H-chromene derivatives. This reaction features a 1,2-difunctionalization of C−C π-bond with two C−H bonds using O2 as terminal oxidant at room temperature. The products obtained are valuable synthons and important scaffolds in biological agents and natural products.