Virological characteristics of hepatitis B genotype G/A2 recombination virus in Japan
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- 作者：Yuji Tsuzuki ; Tsunamasa Watanabe ; Etsuko Iio ; Seiichiro Fujisaki ; Shiro Ibe ; Satomi Kani ; Susumu Hamada-Tsutsumi ; Yoshiyuki Yokomaku ; Yasumasa Iwatani ; Wataru Sugiura ; Chiaki Okuse ; Akihiko Okumura ; Yoshihisa Sato and Yasuhito Tanaka
- 刊名：Hepatology Research
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：46
- 期：8
- 页码：775-783
- 全文大小：867K
- ISSN：1872-034X
文摘
We identified four cases of infection with hepatitis B virus genotype G and A2 recombinant (HBV/G/A2) strains, which were initially overlooked by enzyme immunoassay-based genotyping. The patients were all men who have sex with men (MSM) and inhabited several metropolitan areas of Japan, suggesting that the recombinant strains may be circulating among high-risk groups such as MSM. Here, we investigated the genomic structure and virological properties of the HBV/G/A2 strains.