Whole-exome sequencing of duodenal adenocarcinoma identifies recurrent Wnt/β-catenin signaling pathway mutations

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• 作者：Wei Yuan ; Zhou Zhang ; Binghua Dai ; Qing Wei ; Jinjin Liu ; Yuzhen Liu ; Yun Liu ; Lin He and Daizhan Zhou
• 刊名：Cancer
• 出版年：2016
• 出版时间：June 1, 2016
• 年：2016
• 卷：122
• 期：11
• 页码：1689-1696
• 全文大小：406K
• ISSN：1097-0142

文摘

Genomic alterations of small bowel cancers remain poorly understood due to the rarity of these diseases. In the current study, the authors report the identification of somatic mutations from patients with duodenal adenocarcinoma by whole-exome sequencing.