Diet-induced obese mice exhibit altered immune responses to acute lung injury induced by Escherichia coli

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• 作者：Taomei Wan ; Guiqiang Yuan ; Yi Ren ; Zhicai Zuo ; Zhengyi Wang ; Yiping Jia ; Hengmin Cui ; Xi Peng ; Jing Fang ; Junliang Deng ; Shumin Yu ; Yanchun Hu ; Liuhong Shen ; Xiaoping Ma ; Ya Wang and Zhihua Ren
• 刊名：Obesity
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：24
• 期：10
• 页码：2101-2110
• 全文大小：930K
• ISSN：1930-739X

文摘

Obesity has been associated with impaired immunity and increased susceptibility to bacterial infection. It also exerts protective effects against mortality secondary to acute lung injury. The effects of obesity on immune responses to acute lung injury induced by Escherichia coli were investigated to determine if the above-mentioned differences in its effects were related to infection severity.