BN-9, a chimeric peptide with mixed opioid and neuropeptide FF receptor agonistic properties, produces nontolerance-forming antinociception in mice
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- 作者：Ning Li ; Zheng-lan Han ; Zi-long Wang ; Yan-hong Xing ; Yu-long Sun ; Xu-hui Li ; Jing-jing Song ; Ting Zhang ; Run Zhang ; Meng-na Zhang ; Biao Xu ; Quan Fang and Rui Wang
- 刊名：British Journal of Pharmacology
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：173
- 期：11
- 页码：1864-1880
- 全文大小：1443K
- ISSN：1476-5381
文摘
Neuropeptide FF (NPFF) behaves as an endogenous opioid-modulating peptide. In the present study, the opioid and NPFF pharmacophore-containing chimeric peptide BN-9 was synthesized and pharmacologically characterized.