Pd-Catalyzed C−H Arylation of Benzothiazoles with Diaryliodonium Salt: One-Pot Synthesis of 2-Arylbenzothiazoles

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• 作者：Peng Yang ; Rui Wang ; Hui Wu ; Prof. Dr. Zhengyin Du and Dr. Ying Fu
• 刊名：Asian Journal of Organic Chemistry
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：6
• 期：2
• 页码：184-188
• 全文大小：619K
• ISSN：2193-5815

文摘

A simple and direct arylation of benzothiazoles in the presence of diaryliodonium salts to afford 2-arylbenzothiazoles has been developed. This cross-coupling reaction is catalyzed by palladium bromide in the presence of cesium carbonate and a phosphorus ligand. The protocol has a broad substrate scope and is tolerant towards a wide range of functional groups to give the desired products in moderate to high yields.