In vivo injection of -bungarotoxin to improve the efficiency of motor endplate labeling

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• 作者：Wentao Chen ; Tingting Yu ; Bo Chen ; Yisong Qi ; Peixun Zhang ; Dan Zhu ; Xiaofeng Yin and Baoguo Jiang
• 刊名：Brain and Behavior
• 出版年：2016
• 出版时间：June 2016
• 年：2016
• 卷：6
• 期：6
• 全文大小：1009K
• ISSN：2157-9032

文摘

Motor endplates are composed of a motor neuron terminal and muscle fiber and are distributed in skeletal muscle, causing muscle contraction. However, traditional motor endplate staining methods are limited to the observation of partial skeletal muscle. The procedure was time-consuming due to strict incubation conditions, and usually provided unsatisfactory results. We explored a novel method to label motor endplate rapidly by in vivo injection of fluorescent α-bungarotoxin.