Glucose and lipid effects of the ileal apical sodium-dependent bile acid transporter inhibitor GSK2330672: double-blind randomized trials with type 2 diabetes subjects taking metformin

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• 作者：D. J. Nunez ; X. Yao ; J. Lin ; A. Walker ; P. Zuo ; L. Webster ; S. Krug-Gourley ; M. J. Zamek-Gliszczynski ; D. S. Gillmor and S. L. Johnson
• 刊名：Diabetes, Obesity and Metabolism
• 出版年：2016
• 出版时间：July 2016
• 年：2016
• 卷：18
• 期：7
• 页码：654-662
• 全文大小：645K
• ISSN：1463-1326

文摘

To investigate the pharmacodynamics, pharmacokinetics and safety/tolerability of blocking reuptake of bile acids using the inhibitor GSK2330672 (GSK672) in patients with type 2 diabetes (T2D).