Evaluation of the Cellular and Animal Models for the Study of Antioxidant Activity: A Review

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• 作者：Huijuan Zhang ; Meng Yin ; Lianyan Huang ; Jing Wang ; Lingxiao Gong ; Jie Liu and Baoguo Sun
• 刊名：Journal of Food Science
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：82
• 期：2
• 页码：278-288
• 全文大小：397K
• ISSN：1750-3841

文摘

The mechanisms of antioxidant activities of phytochemicals are highly complex, so various methods to study them have been developed. However, the diverse available methods show inconsistent results. Different stressors, cell models, and animal models have been used to evaluate the antioxidant properties of phytochemicals. However, the literature still lacks a summary of the effects of different stressors, cell models, and animal models on the evaluation of antioxidant activities. Therefore, the mechanisms of action of different oxidative stimuli and the characteristics of the available cell models and animal models are summarized in this review.