Hydrodehalogenation of Haloarenes by a Sodium Hydride-Iodide Composite

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• 作者：Derek Yiren Ong ; Dr. Ciputra Tejo ; Kai Xu ; Prof. Hajime Hirao and Prof. Shunsuke Chiba
• 刊名：Angewandte Chemie International Edition
• 出版年：2017
• 出版时间：February 6, 2017
• 年：2017
• 卷：56
• 期：7
• 页码：1840-1844
• 全文大小：993K
• ISSN：1521-3773

文摘

A simple protocol for hydrodebromination and -deiodination of halo(hetero)arenes was enabled by sodium hydride (NaH) in the presence of lithium iodide (LiI). Mechanistic studies showed that an unusual concerted nucleophilic aromatic substitution operates in the present process.