Polydopamine Hollow Nanoparticle Functionalized with N-diazeniumdiolates as a Nitric Oxide Delivery Carrier for Antibacterial Therapy
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- 作者：Dongsik Park ; Jihoon Kim ; Yeong Mi Lee ; Junghong Park and Won Jong Kim
- 刊名：Advanced Healthcare Materials
- 出版年：2016
- 出版时间：August 24, 2016
- 年：2016
- 卷：5
- 期：16
- 页码：2019-2024
- 全文大小：1593K
- ISSN：2192-2659
文摘
A biocompatible nitric oxide (NO) delivery nanoplatform, whose structure is a hollow nanoparticle composed of polydopamine backbone and diazeniumdiolates functional groups, is developed for antibacterial therapy. This platform liberates high NO quantitis and exerts the antibacterial activity with excellent biocompatibility thus being promising for treating bacterial infections.