We describe a three-step one-pot metal-free domino procedure yieldin
g a set of boscalid derivatives, pa
rent compound bein
g a hi
ghly important a
grochemical a
gent. The first step of the process consists of the
Diels–Alder reaction between a substituted
2H-pyran-2-one and sty
rene derivatives, followed by the elimination of CO
2 and
aromatization (oxidation). The last step was found to be efficiently promoted by the application of
chloranil as the oxidant. Alternatively,
activated carbon Darco KB could also act as the
dehydrogenation catalyst necessitatin
g a lar
ger excess of the
render" xmlns:mml="http://www.w3.org/1998/Math/MathML" id="jhet2603-eo-0011">styrene to act as the hydro
gen acceptor.