An Expedient Synthesis of Carbazoles through Potassium tert-Butoxide-Promoted Intramolecular Direct C-H Bond Arylation
详细信息 查看全文
- 作者：Songbo Lin ; Xingrui He ; Jinpeng Meng ; Haining Gu ; Peizhi Zhang and Jun Wu
- 刊名：European Journal of Organic Chemistry
- 出版年：2017
- 出版时间：January 18, 2017
- 年：2017
- 卷：2017
- 期：3
- 页码：443-447
- 全文大小：895K
- ISSN：1099-0690
文摘
Transition-metal-free access to carbazoles was achieved through base-mediated intramolecular C–C bond formation. Reactions of N-substituted o-halodiarylamines with potassium tert-butoxide in the presence of ethylene glycol or 1,10-phenanthroline provided carbazoles in moderate to excellent yields. This transformation may proceed through a radical pathway according to a control experiment with a radical scavenger.