Estimations and predictors of non-compliance in switchers to reduced nicotine content cigarettes

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• 作者：Natalie Nardone ; Eric C. Donny ; Dorothy K. Hatsukami ; Joseph S. Koopmeiners ; Sharon E. Murphy ; Andrew A. Strasser ; Jennifer W. Tidey ; Ryan Vandrey and Neal L. Benowitz
• 刊名：Addiction
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：111
• 期：12
• 页码：2208-2216
• 全文大小：1657K
• ISSN：1360-0443

文摘

Clinical trials on the impact and safety of reduced nicotine content cigarettes (RNCs) are ongoing, and an important methodological concern is participant compliance with smoking only RNCs. Our aims were to measure non-compliance biochemically with urine cotinine (COT) and total nicotine equivalents (TNEs), compare with self-reported non-compliance and identify associated covariates.