Periostin as a biomarker for the diagnosis of pediatric asthma
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- 作者：Takashi Inoue ; Kenichi Akashi ; Masako Watanabe ; Yuichi Ikeda ; Shuichi Ashizuka ; Takanori Motoki ; Ryohei Suzuki ; Nagatoshi Sagara ; Noriyuki Yanagida ; Sakura Sato ; Motohiro Ebisawa ; Shoichiro Ohta ; Jyunya Ono ; Kenji Izuhara and Toshio Katsunuma
- 刊名：Pediatric Allergy and Immunology
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：27
- 期：5
- 页码：521-526
- 全文大小：249K
- ISSN：1399-3038
文摘
There are some biomarkers for asthma diagnosis but they are often difficult in clinical use, particularly in pediatric cases. Periostin is an extracellular matrix protein, upregulated in response to IL-4 or IL-13. Serum periostin is expected to be used as a non-invasive biomarker for asthma diagnosis and management.