ChemInform Abstract: Chemoselective Switch in the Asymmetric Organocatalysis of 5H-Oxazol-4-ones and N-Itaconimides: Addition—Protonation or [4 + 2] Cycloaddition.
The use of chiral urea catalysts allow the selective formation of [4 + 2] cycloaddition products or tandem conjugate addition protonation products with high diastereo- and enantioselectivities.