Increased autophagy is required to protect periodontal ligament stem cells from apoptosis in inflammatory microenvironment
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- 作者：Ying An ; Wenjia Liu ; Peng Xue ; Yongjie Zhang ; Qintao Wang and Yan Jin
- 刊名：Journal of Clinical Periodontology
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：43
- 期：7
- 页码：618-625
- 全文大小：859K
- ISSN：1600-051X
文摘
Autophagy, which provides a mechanism for turnover cellular organelles and proteins through a lysosome-dependent degradation pathway, has been related to the pathogenesis of inflammatory disorders and other diseases. Therefore, the aim of this research was to study the role of autophagy in periodontal ligament stem cells (PDLSCs) and provide a new strategy for treatment or prevention of periodontitis.