Biocompatibility and physicochemical characteristics of poly(Ɛ-caprolactone)/poly(lactide-co-glycolide)/nano-hydroxyapatite composite scaffolds for bone tissue engineering

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• 作者：Xin Li^a ; ^b ; Shujiang Zhang^a ; ^{zhangshj@lzu.edu.cn} ; Xiao Zhang^b ; Siyu Xie^b ; Guanghui Zhao^a ; Lifen Zhang^a
• 关键词：Poly(Ɛ-caprolactone) ; Poly(lactide-co-glycolide) ; Melt-blending/particle-leaching ; Human bone marrow mesenchymal stem cells ; Bone tissue engineering
• 刊名：Materials & Design
• 出版年：2017
• 出版时间：15 January 2017
• 年：2017
• 卷：114
• 期：Complete
• 页码：149-160
• 全文大小：4049 K
• 卷排序：114

文摘

The biomaterial scaffold in the study was fabricated through melt-blending/particle-leaching process for the first time. The scaffold material can promote the proliferation and differentiation of human mesenchymal stem cells. The scaffold material might be a promising biomaterial in the bone regeneration engineering.