文摘
This paper deals with a free boundary problem modeling tumor growth with inhibitors. This problem has a unique radially symmetric stationary solution with radius ext stixSupport mathImg" data-mathURL="/science?_ob=MathURL&_method=retrieve&_eid=1-s2.0-S1468121814000364&_mathId=si1.gif&_user=111111111&_pii=S1468121814000364&_rdoc=1&_issn=14681218&md5=bb40d26cdd14c1c9983893d24a1a3607" title="Click to view the MathML source">r=Rser hidden">e">. The tumor aggressiveness is modeled by a positive tumor aggressiveness parameter ext stixSupport mathImg" data-mathURL="/science?_ob=MathURL&_method=retrieve&_eid=1-s2.0-S1468121814000364&_mathId=si2.gif&_user=111111111&_pii=S1468121814000364&_rdoc=1&_issn=14681218&md5=d2932716809e5725a7d5163ca552d9cd" title="Click to view the MathML source">渭er hidden">e">. It is shown that there exist a positive integer ext stixSupport mathImg" data-mathURL="/science?_ob=MathURL&_method=retrieve&_eid=1-s2.0-S1468121814000364&_mathId=si3.gif&_user=111111111&_pii=S1468121814000364&_rdoc=1&_issn=14681218&md5=f157822367a6db2e9393ae98ebda71f8" title="Click to view the MathML source">m∗∗∈Rer hidden">e"> and a sequence of ext stixSupport mathImg" data-mathURL="/science?_ob=MathURL&_method=retrieve&_eid=1-s2.0-S1468121814000364&_mathId=si4.gif&_user=111111111&_pii=S1468121814000364&_rdoc=1&_issn=14681218&md5=a628417831a579844e5b52aabe629922" title="Click to view the MathML source">渭mer hidden">e">, such that for eachext stixSupport mathImg" data-mathURL="/science?_ob=MathURL&_method=retrieve&_eid=1-s2.0-S1468121814000364&_mathId=si5.gif&_user=111111111&_pii=S1468121814000364&_rdoc=1&_issn=14681218&md5=c2197e97c45681ddb653ee6ba9c24d07" title="Click to view the MathML source">渭m(m>m∗∗)er hidden">e">, symmetry-breaking solutions bifurcate from the radially symmetric stationary solutions.