Label-free quantitative proteomic analysis of benzo(a)pyrene-transformed 16HBE cells serum-free culture supernatant and xenografted nude mice sera
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- 作者：Peng Zhaoa ; b ; zhaopeng@bjmu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Juanling Fua ; Biyun Yaoa ; b ; Yongrui Jiac ; Hongtao Zhanga ; b ; Xuehui Lia ; b ; Lisha Donga ; b ; Ya Gaoa ; b ; Wenli Liua ; b ; Wen Chend ; Zongcan Zhoua ; zhouzc@bjmu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Label-free quantitative proteomics ; NRP2 ; CLU ; AKAP12 ; Benzo(a)pyrene ; T-16HBE-C1 cells
- 刊名：Chemico-Biological Interactions
- 出版年：2016
- 出版时间：5 February 2016
- 年：2016
- 卷：245
- 期：Complete
- 页码：39-49
- 全文大小：3404 K
文摘
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Benzo(a)pyrene-transformed 16HBE cell line T-16HBE-C1 was used as a study model.
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Quantitative proteomic analysis of cell culture media and xenografted nude mice sera.
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The serum NRP2 levels positively correlate with the tumor growth.
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Serum NRP2, CLU and AKAP12 could be potential biomarkers of BaP-induced lung cancer.