Molecular recognition between adenine or 2,6-diaminopurine and copper(II) chelates with N,O2,S-tripodal tetradentate chelators having thioether or disulfide donor groups
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- 作者：Josefa Marí ; a Gonzá ; lez-Pé ; reza ; jmgp@ugr.es" class="auth_mail" title="E-mail the corresponding author ; Duane Choquesillo-Lazarteb ; Alicia Domí ; nguez-Martí ; na ; 1 ; alicia.dominguez@chem.uzh.ch" class="auth_mail" title="E-mail the corresponding author ; Hanan El Bakkalia ; Marí ; a Eugenia Garcí ; a-Rubiñ ; oc ; Inmaculada Pé ; rez-Toroa ; Ester Ví ; lchez-Rodrí ; gueza ; Alfonso Castiñ ; eirasd ; Valeria Marina Nurchie ; Juan Nicló ; s-Gutié ; rreza
- 关键词：Copper(II) complexes ; Thioether ; Disulfide ; Interligand interactions ; Adenine
- 刊名：Journal of Inorganic Biochemistry
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：151
- 期：Complete
- 页码：75-86
- 全文大小：1456 K
文摘
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N,O2,S-tripodal Cu(II) chelates bind adenine (Hade) or 2,6-diaminopurine (Hdap).
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The N-branched topology of the chelators strongly favors the formation of Cu–S bonds.
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The S(thioether or disulfide) donor occupies a distal site in Cu(II) coordination.
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N7-H(N9)ade, μ2-N3,N7-H(N9)ade or μ2-N7,N9-H(N3)dap modes are reported.
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Cu–N(purine) bonds cooperate with intra-molecular N–H⋯O interligand interactions.