Protection of flavonoids from Smilax china L. rhizome on phenol mucilage-induced pelvic inflammation in rats by attenuating inflammation and fibrosis

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• 作者：Luyao Song^a ; ¹ ; Liwen Tian^b ; ¹ ; Yun Ma^a ; Yang Xie^b ; Haixing Feng^a ; Fei Qin^c ; Liqian Mo^a ; Si Lin^d ; Lianbing Hou^a ; ^b ; ^{lianbingh@hotmail.com} ; Chunxia Wang^a ; ^{wcxia@hotmail.com}
• 关键词：Chlorogenic acid (PubChem CID ; 1794427) ; Astilbin (PubChem CID ; 119258) ; Isoastilbin (PubChem CID ; 9981176) ; Quercetin-3-O-α-l-rhamnopyranoside (PubChem CID ; 5280459) ; Cinchonain Ia (PubChem CID ; 10456516) ; Engeletin (PubChem CID ; 6453452) ; Isoengeletin (PubChem CID ; 101937309)
• 刊名：Journal of Functional Foods
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：28
• 期：Complete
• 页码：194-204
• 全文大小：5791 K
• 卷排序：28

文摘

The chemical compositions of FSCR were analysed by UPLC-PDA-MS. A PID model induced by phenol mucilage was successfully established in rats. The effects of FSCR on rats with PID were studied. FSCR attenuated pelvic inflammation and prevented fibrosis. The ERK1/2 and Smad2/3 signalling pathways may be involved in the effects of FSCR.