CacyBP/SIP — Structure and variety of functions
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- 作者：Agnieszka M. Topolska-Wośa ; Walter J. Chazinb ; c ; d ; Anna Filipeka ; a.filipek@nencki.gov.pl" class="auth_mail" title="E-mail the corresponding author
- 关键词：AD ; Alzheimer's disease ; AEDANS ; (5-((((2-iodoacetyl)amino)ethyl)amino)-naphthalene-1-sulfonic acid) ; CacyBP/SIP ; Calcyclin-Binding Protein and Siah-1 Interacting Protein ; CD ; circular dichroism ; CHORD ; Cysteine and histidine-rich domain ; CKII ; casein kinase II ; CS domain ; central domain of CacyBP/SIP ; Elk-1 ; transcription factor ; ERK1/2 ; extracellular signal regulated kinases 1 and 2 ; HCT116 ; human colon carcinoma cell line ; KIM ; kinase interaction motif ; NB2a and SH-SY5Y ; mouse and human neuro
- 刊名：Biochimica et Biophysica Acta (BBA) - General Subjects
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：1860
- 期：1
- 页码：79-85
- 全文大小：605 K
文摘
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CacyBP/SIP is expressed in different tissues of mammals and of lower organisms.
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CacyBP/SIP is a multi-domain protein that binds several targets.
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CacyBP/SIP is implicated in a wide range of cellular processes.
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Changes in CacyBP/SIP level are observed in many cancers.
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Changes in neuronal localization of CacyBP/SIP are associated with neurodegeneration.