We combine results about Whitehead groups of finite groups with results about genetic bases of finite p-groups to compute the Whitehead groups of some metacyclic p -groups. Let a50d73ba473d75d835e4ae288a94bd82" title="Click to view the MathML source">Cpn denote a cyclic group of order pn for p an odd prime and n a positive integer. We present a conjecture for the torsion part of the Whitehead group of Cpn×Cpn and we show that torsion part of the Whitehead group of the semidirect product of Cpn−1 by Cp is isomorphic to 78a8289ee">. The techniques we use can be applied to any abelian p-group and to many other p-groups for p odd.