Lipoprotein-associated phospholipase A2 in coronary heart disease: Review and meta-analysis

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• 作者：Dongze Li^a ; ¹ ; Lizhi Zhao^b ; ¹ ; Jing Yu^c ; ¹ ; Wei Zhang^a ; Rongsheng Du^c ; Xin Liu^d ; Ying Liu^e ; You Chen^f ; Rui Zeng^c ; Yu Cao^a ; Zhi Zeng^a ; Zhiwei Zhao^g ; ^{zzw2002400@126.com} ; Jiang Wu^g ; ^{jw@scu.edu.cn}
• 关键词：Lp-PLA2 ; lipoprotein-associated phospholipase A2 ; ACS ; acute coronary syndrome ; CHD ; coronary heart disease ; HR ; hazard ratio ; CI ; confidence interval ; LDL ; low-density lipoprotein
• 刊名：Clinica Chimica Acta
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：465
• 期：Complete
• 页码：22-29
• 全文大小：458 K
• 卷排序：465

文摘

Lp-PLA2 was not related to all-cause mortality in coronary heart disease (CHD). Higher Lp-PLA2 was significantly associated with increased cardiovascular events risk in (CHD). It was superior for Lp-PLA2 predicting cardiovascular events in patients with stable (CHD) or without receiving therapies of inhibiting Lp-PLA2. Lp-PLA2 was a vascular-specific inflammatory biomarker to stratify the high-risk patients with (CHD).