Management of carotid body tumor in pediatric patients: A case report and review of the literature

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• 作者：Apanisile Ifeoluwa^a ; Istv&aacute ; n L&aacute ; z&aacute ; r^b ; É ; va Szö ; vö ; rdi^c ; Tam&aacute ; s Karosi^a ; ^{karositamas@gmail.com}
• 关键词：Carotid body tumor ; Embolization ; Neuroradiology ; Paragangliomas
• 刊名：International Journal of Pediatric Otorhinolaryngology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：93
• 期：Complete
• 页码：47-52
• 全文大小：2333 K
• 卷排序：93

文摘

Carotid body tumors (CBTs) are rare types of extra-adrenal paragangliomas, which originate from the neuroendocrine cells of the adventitial layer of carotid bifurcation. An 8-year-old girl was admitted to our department with left-sided and pulsating neck swelling, which progressively grew over several months. The patient had no family history of CBTs. Computed tomography (CT) and CT angiography (CTA) scans revealed a contrast material enhancing, hypervascularized mass involving the left carotid bifurcation, internal carotid artery (ICA), and external carotid artery (ECA), respectively. Preoperative embolization and surgical resection were performed. Histopathological examination later confirmed a benign CBT. Current follow-up examination revealed no evidence of residual or recurrent tumor. A systemic review of the literature indicates that early diagnosis, and experienced multi-disciplinary management is required in case of unilateral, resectable forms of CBTs with no distant metastasis, in order to provide a long-time survival of patients. Surgical intervention of unilateral, solitary CBTs with preoperative embolization is a relatively safe procedure, allowing complete tumor removal with minimal morbidity and low recurrence rate.