Stable isotope dilution ultra-high performance liquid chromatography-tandem mass spectrometry quantitative profiling of tryptophan-related neuroactive substances in human serum and cerebrospinal fluid
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- 作者：Eva Hé ; nyková ; a ; Hana Přikrylová ; Vrá ; nová ; b ; Petra Amakorová ; a ; Tomá ; &scaron ; Pospí ; &scaron ; ilc ; Asta Žukauskaitėa ; d ; Magdalé ; na Vlčková ; a ; Lubor Urbá ; neka ; Ondřej Nová ; ka ; novako@ueb.cas.cz" class="auth_mail" title="E-mail the corresponding author ; Jan Mare&scaron ; b ; Petr Kaňovský ; b ; Miroslav Strnada ; miroslav.strnad@upol.cz" class="auth_mail" title="E-mail the corresponding author
- 关键词：Tryptophan metabolism ; UHPLC&ndash ; MS/MS ; Neurochemicals ; Serum ; Cerebrospinal fluid
- 刊名：Journal of Chromatography A
- 出版年：2016
- 出版时间：11 March 2016
- 年：2016
- 卷：1437
- 期：Complete
- 页码：145-157
- 全文大小：1429 K
文摘
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Profiling of L-tryptophan (L-TRP) and its related compounds in human bodily fluids.
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Simultaneous determination of endogenous L-TRP and its 16 metabolites by LC–MS/MS.
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Isotope dilution mass spectrometry—17 isotope labelled internal standards used.