New silver complexes with bioactive glycine and nicotinamide molecules - Characterization, DNA binding, antimicrobial and anticancer evaluation

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• 作者：Michaela Rendo&scaron ; ov&aacute ; ^a ; Zuzana Vargov&aacute ; ^a ; ^{zuzana.vargova@upjs.sk} ; Juraj Kuch&aacute ; r^a ; Danica Sabolov&aacute ; ^b ; &Scaron ; tefan Levoča^b ; Jú ; lia Kudl&aacute ; čov&aacute ; ^b ; Helena Paulí ; kov&aacute ; ^c ; Daniela Hudecov&aacute ; ^c ; Veronika Helebrandtov&aacute ; ^c ; Miroslav Alm&aacute ; &scaron ; i^a ; M&aacute ; ria Vilkov&aacute ; ^d ; Michal Du&scaron ; ek^e ; D&aacute ; &scaron ; a Bob&aacute ; ľov&aacute ; ^a
• 关键词：Silver complex ; Antimicrobial effect ; Stability ; Cytotoxicity ; Intercalation ; Topo I and II inhibition assay
• 刊名：Journal of Inorganic Biochemistry
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：168
• 期：Complete
• 页码：1-12
• 全文大小：1100 K
• 卷排序：168

文摘

Novel Ag(I) complexes were prepared and characterized. Antimicrobial and anticancer testing was accomplished. DNA binding properties and cytotoxic mechanism were investigated.