Silver nanoparticles strongly enhance and restore bactericidal activity of inactive antibiotics against multiresistant Enterobacteriaceae
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- 作者：Ale&scaron ; Paná ; čeka ; ales.panacek@upol.cz" class="auth_mail" title="E-mail the corresponding author ; Monika Smé ; kalová ; a ; Renata Večeřová ; b ; Kateřina Bogdanová ; b ; Magdalé ; na Rö ; derová ; b ; Milan Kolá ; řb ; Martina Kilianová ; a ; &Scaron ; á ; rka Hradilová ; a ; Jens P. Froninga ; Marké ; ta Havrdová ; c ; Robert Pruceka ; Radek Zbořila ; Libor Kví ; teka
- 关键词：Silver nanoparticle ; Antibiotic ; Resistant bacteria ; Synergism ; Cytotoxicity
- 刊名：Colloids and Surfaces B: Biointerfaces
- 出版年：2016
- 出版时间：1 June 2016
- 年：2016
- 卷：142
- 期：Complete
- 页码：392-399
- 全文大小：1215 K
文摘
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Silver NPs restore bactericidal effect of antibiotics against resistant bacteria.
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Double disk synergy test did not prove beta-lactamase production in bacteria.
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Rigidity of bacterial cell wall was affected by restored antibiotic’s activity.
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Antibiotics combined with silver NPs showed no cytotoxic effect to mammalian cells.