IC50 values of Cu(II) complexes tested on MCF-7 cancer cells increased in a time- dependent manner.
Noncancer cells were not sensitive to Cu(II) complexes.
In MCF-7 cells Cu(II) complexes induced condensation and asymmetric conformational changes in actin filaments.
Cu(II) complexes did not induce apoptosis in MCF-7.
Cu(II) complexes induced autophagy in MCF-7.