Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells

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• 作者：Hajime Ishinaga^a ; ¹ ; ^{hajime@clin.medic.mie-u.ac.jp} ; Masako Kitano^a ; ¹ ; Masaaki Toda^b ; Corina N. D&rsquo ; Alessandro-Gabazza^b ; Esteban C. Gabazza^b ; Said Ahmad Shah^a ; Kazuhiko Takeuchi^a
• 关键词：IL-33 ; IL-13 ; MUC5AC ; Goblet cell hyperplasia
• 刊名：Cytokine
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：90
• 期：Complete
• 页码：60-65
• 全文大小：861 K
• 卷排序：90

文摘

IL-33 was upregulated in nasal polyps of eosinophilic chronic rhinosinusitis. IL-33 increase MUC5AC gene and MUC5AC protein in primary human nasal epithelial cell. IL-33 induces goblet cell hyperplasia in primary human nasal epithelial cell.