Genotyping of pathogenic Acanthamoebae isolated from clinical samples in Greece—Report of a clinical isolate presenting T5 genotype

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• 作者：G. Spanakos ; K. Tzanetou ; D. Miltsakakis ; E. Patsoula ; E. Malamou-Lada and N.C. Vakalis
• 关键词：Acanthamoeba ; Genotyping ; Greece
• 刊名：Parasitology International
• 出版年：2006
• 出版时间：June 2006
• 年：2006
• 卷：55
• 期：2
• 页码：147-149
• 全文大小：89 K

文摘

Amoebae belonging to the genus Acanthamoeba are potentially pathogenic to humans, causing mainly amoebic keratitis. Pathogenic ability of the 15 known Acanthamoeba genotypes is under investigation. We report that four out of five cases of amoebic keratitis studied in Greece, present T4 sequence type, while the remaining one presents T5 sequence type (Acanthamoeba lenticulata), which is the second most frequent genotype found among environmental samples. Thus, it is confirmed, for the first time to our knowledge, that A. lenticulata can cause keratitis. However the reason that it is under represented in clinical samples compared to environmental ones is unknown.