Anxiolytic properties of N-acetylcysteine in mice
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- 作者：Patrí ; cia Santosa ; b ; Ana P. Herrmannc ; Radharani Benvenuttia ; b ; Guilherme Noetzolda ; Franciele Giongoa ; Clarissa S. Gamad ; e ; Angelo L. Piatob ; Elaine Elisabetskya ; b ; elaine.elisabetsky@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：N-acetylcysteine (NAC) ; Open field ; Light/dark ; Hole-board ; Social interaction ; Stress-induced hyperthermia
- 刊名：Behavioural Brain Research
- 出版年：2017
- 出版时间：15 January 2017
- 年：2017
- 卷：317
- 期：Complete
- 页码：461-469
- 全文大小：1634 K
文摘
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NAC shows anxiolytic effects on five mice models of anxiety.
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Subacute NAC results in lower effective anxiolytic doses than acute treatment.
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Anxiolytic doses of NAC do not affect locomotion.