Alteration of α-N-acetylgalactosaminidase (nagalase) concentration in alcohol-dependent individuals without liver disease, during the detoxification therapy

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• 作者：Margarita Zoga^a ; Thomas Nikou^b ; Anastasios Ioannidis^a ; ^c ; Elias Tzavellas^b ; Thomas Paparrigopoulos^b ; Konstantinos Th. Lambrokostopoulos^d ; Vassilis G. Vasdekis^d ; Maria Magana^a ; Stylianos Chatzipanagiotou^a ; ^{schatzipa@gmail.com} ; ^{schatzi@med.uoa.gr}
• 关键词：α-N-acetylgalactosaminidase ; Nagalase ; Alcohol abuse ; Macrophage-activating factor ; MAF
• 刊名：Drug and Alcohol Dependence
• 出版年：2017
• 出版时间：1 January 2017
• 年：2017
• 卷：170
• 期：Complete
• 页码：147-151
• 全文大小：426 K
• 卷排序：170

文摘

Nagalase was determined in alcoholics, during detoxification therapy. Nagalase was elevated in all serum collections compared to the normal controls. There was a progressive fall from admission to discharge. High nagalase concentrations might be associated with macrophage impairment. Nagalase could serve as a marker of alcohol overconsumption.