文摘
Sox2, Olig2, and Zeb1 expression is increased in glioma-initiating cells These transcription factors are expressed irrespective of putative GBM oncogenes Sox2, Olig2, and Zeb1 expression transforms tumor-suppressor-deficient astrocytes Mithramycin inhibits Sox2, Olig2, and Zeb1 expression and GBM cell proliferation