Intermolecular interactions of l-glutamine and l-histidine in aqueous solutions of metformin hydrochloride: Thermo-acoustic and optical properties
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- 作者：S. Chauhana ; scschauhsan19@gmail.com" class="auth_mail" title="E-mail the corresponding author ; K. Singha ; M.S. Chauhana ; Ahmad Umarb ; ahmadumar786@gmail.com" class="auth_mail" title="E-mail the corresponding author ; C.N. Sundaresanc
- 关键词：Metformin hydrochloride ; Intermolecular free length ; Specific acoustic impedance ; Molar cohesive energy ; UV&ndash ; Vis studies
- 刊名：Journal of Molecular Liquids
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：214
- 期：Complete
- 页码：390-399
- 全文大小：2166 K
文摘
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Temperature dependent acoustic and UV–Vis studies for drug–AA system have been carried out.
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Intermolecular interactions in aqueous metformin hydrochloride–amino acid system have been investigated.
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Strong solute–solvent interactions of the type dipole–dipole through H-bonding have been observed.
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These interactions are stronger for histidine as compare to glutamine.
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Bathochromic shift for both amino acids has been observed.