ZMYND8 Reads the Dual Histone Mark H3K4me1-H3K14ac to Antagonize the Expression of Metastasis-Linked Genes
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- 作者：Na Li1 ; 14 ; Yuanyuan Li2 ; 3 ; 14 ; Jie Lv4 ; 5 ; 6 ; 14 ; Xiangdong Zheng2 ; 3 ; Hong Wen7 ; Hongjie Shen8 ; Guangjing Zhu9 ; Tsai-Yu Chen1 ; Shilpa S. Dhar1 ; Pu-Yeh Kan1 ; Zhibin Wang9 ; Ramin Shiekhattar10 ; Xiaobing Shi7 ; Fei Lan8 ; Kaifu Chen4 ; 5 ; 6 ; Wei Li11 ; WL1@bcm.edu" class="auth_mail" title="E-mail the corresponding author ; Haitao Li2 ; 3 ; 12 ; lht@tsinghua.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Min Gyu Lee1 ; 13 ; 15 ; mglee@mdanderson.org" class="auth_mail" title="E-mail the corresponding author
- 刊名：Molecular Cell
- 出版年：2016
- 出版时间：4 August 2016
- 年：2016
- 卷：63
- 期：3
- 页码：470-484
- 全文大小：4234 K
文摘
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ZMYND8 acts as a JARID1D corepressor for JARID1D-mediated gene repression
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PHD-Bromo in ZMYND8 reads H3K4me1-H3K14ac and H3K4me0-H3K14ac
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ZMYND8 has an anti-metastasis function
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H3K4me1-H3K14ac is associated with repression of metastasis-linked genes