Molecularly imprinted polymer nanomaterials and nanocomposites by controlled/living radical polymerization

详细信息    查看全文

• 作者：Selim Beyazit ; Bernadette Tse Sum Bui ; Karsten Haupt ; ^{karsten.haupt@utc.fr} ; Carlo Gonzato ; ^{carlo.gonzato@utc.fr}
• 关键词：2 ; 4-D ; 2 ; 4-dichlorophenoxyacetic acid ; 4-VP ; 4-vinylpyridine ; AAm ; acrylamide ; AIBN ; azobisisobutyronitrile ; ATRA ; atom transfer radical addition ; ATRP ; atom transfer radical polymerization ; BDC ; benzyl diethyldithiocarbamate ; BET ; Brunauer&ndash ; Emmett&ndash ; Teller ; CNT ; carbon nanotube ; CRP ; controlled radical polymerization ; DEAEM ; diethylaminoethyl methacrylate ; DLS ; dynamic light scattering ; DSDMA ; bis(2-methacryloyloxyethyl) disulfide ; DVB ; divinylbenzene ; EGDMA ; ethylene glycol dimethacry
• 刊名：Progress in Polymer Science
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：62
• 期：Complete
• 页码：1-21
• 全文大小：4497 K
• 卷排序：62

文摘

Since the pioneering work of Wulff and Mosbach more than 30 years ago, molecular imprinting of synthetic polymers has emerged as a robust and convenient way for synthesizing polymeric receptor materials bearing specific recognition sites for target molecules. The resulting materials, molecularly imprinted polymers (MIPs), are therefore commonly referred to as ‘plastic antibodies’. They are obtained by polymerizing a scaffold around a target, or a derivate thereof, which acts as a molecular template. MIPs have been successfully applied in many areas including affinity separation, immunoassays, chemical sensing, solid-phase extraction, drug delivery, cell and tissue imaging, direct synthesis and catalysis. In terms of affinity and selectivity, MIPs are on a par with biological receptors like antibodies, and this is accompanied by a superior chemical and physical stability, compatibility with organic media, reusability, easy engineering and low cost. These advantages represent the main reasons for the wide interest raised around molecularly imprinted materials. Mainly produced by free radical polymerization (FRP) of vinyl monomers, MIPs have also taken advantage of the introduction of controlled/living radical polymerization (CRP) techniques, which have literally transformed polymer chemistry over the last decade. This review describes the advantages arising from the use of CRP in synthesizing MIPs, both in terms of sheer binding properties as well as for their remarkable potential for post-polymerization functionalization, for the synthesis of MIP nanomaterials and for the integration of MIPs into composites and hybrid materials. The benefits of using CRP are critically assessed with respect to the still largely applied FRP and guidelines are provided for choosing the most convenient technique to fit a specific targeted application of MIPs.