Unirradiated cells rescue cells exposed to ionizing radiation: Activation of NF-κB pathway in irradiated cells
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- 作者：R.K.K. Lama ; Wei Hanb ; K.N. Yua ; c ; peter.yu@cityu.edu.hk" class="auth_mail" title="E-mail the corresponding author
- 关键词：Rescue effect ; Radiation-induced bystander effect ; Alpha particles ; NF-κB ; BAY-11-7082 ; Anti-NF-κB
- 刊名：Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：782
- 期：Complete
- 页码：23-33
- 全文大小：2662 K
文摘
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Rescue effect was observed in both irradiated and HeLa and NIH/3T3 cells.
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Novel setup and procedures to separate the rescue signals and the bystander signals.
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Confirmed activation of NF-κB pathway in rescue effect using activation inhibitor.
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Confirmed activation of NF-κB pathway in rescue effect using anti-NF-κB p65 antibody.