Relationship between fluoride exposure and osteoclast markers during RANKL-induced osteoclast differentiation
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- 作者：Pei Junrui1 ; Li Bingyun1 ; Gao Yanhui ; Jiaxun Xu ; Gottfried M. Darko ; Sun Dianjun ; hrbmusdj@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Fluoride ; Osteoclast ; Matrix metalloproteinase 9 (MMP9) ; Cathepsin K (CK) ; Biomarker
- 刊名：Environmental Toxicology and Pharmacology
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：46
- 期：Complete
- 页码：241-245
- 全文大小：1148 K
文摘
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The fluoride exposure significantly correlates with osteoclast markers.
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MMP9 and CK may reflect not only the activity of osteoclast but also the degree of fluoride exposure.
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TRAP5b, CTR and OSCAR are closely correlated with the number of osteoclast formed.